The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Dec. 20, 1999
Mary F. Fitzgerald, Oxon, GB;
Philip J. Gardiner, High Wycombe, GB;
Kevin Nash, Burnham Slough, GB;
Graham Sturton, Maidenhead, GB;
Günter Benz, Velbert, DE;
Rolf Henning, Wuppertal, DE;
Karl-heinz Schlemmer, Wuppertal, DE;
Bernd Riedl, Wuppertal, DE;
Helmut Haning, Wuppertal, DE;
Lorenz Mayr, Weil am Rhein, DE;
Mary F. Fitzgerald, Oxon, GB;
Philip J. Gardiner, High Wycombe, GB;
Kevin Nash, Burnham Slough, GB;
Graham Sturton, Maidenhead, GB;
Günter Benz, Velbert, DE;
Rolf Henning, Wuppertal, DE;
Karl-Heinz Schlemmer, Wuppertal, DE;
Bernd Riedl, Wuppertal, DE;
Helmut Haning, Wuppertal, DE;
Lorenz Mayr, Weil am Rhein, DE;
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
Novel 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives, use of substituted 4-Biarylbutyric and 5-Biarylpentanoic Acid Derivatives as Matrix Metalloprotease Inhibitors for the Treatment of Respiratory Diseases, pharmaceutical compositions containing them, and a process for using them. The compounds of the invention have the generalized formula (I) (T)A—B—D—E—COH wherein A is an aryl or heteroaryl rings; B is an aryl or heteroaryl ring or a bond; each T is a substituent group, x is 0, 1, or 2; the group D represents (a), (b), (c), or (d); the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formation, possible structures being shown in the text and claims; and each of the substituents on E is an independent substituent; and include pharmaceutically acceptable salts thereof.