The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Nov. 13, 1995
Wallace H. Coulter, Miami, FL (US);
Robert K. Zwerner, Ft. Lauderdale, FL (US);
Robert J. Schmittling, Cooper City, FL (US);
Thomas R. Russell, Miami, FL (US);
Wallace H. Coulter, Miami, FL (US);
Robert K. Zwerner, Ft. Lauderdale, FL (US);
Robert J. Schmittling, Cooper City, FL (US);
Thomas R. Russell, Miami, FL (US);
Miltenyi Biotec GmbH, Bergisch Gladbach, DE (US);
Abstract
A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps.