The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Feb. 06, 2001
Yingyos Avihingsanon, Boston, MA (US);
Nali MA, Wirchester, MA (US);
Terry B. Strom, Brookline, MA (US);
Miguel C. Soares, Boston, MA (US);
Christiane Ferran, Brookline, MA (US);
Manikkam Suthanthiran, Scarsdale, NY (US);
Yingyos Avihingsanon, Boston, MA (US);
Nali Ma, Wirchester, MA (US);
Terry B. Strom, Brookline, MA (US);
Miguel C. Soares, Boston, MA (US);
Christiane Ferran, Brookline, MA (US);
Manikkam Suthanthiran, Scarsdale, NY (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Cornell Research Foundation, Inc., Ithaca, NY (US);
Abstract
The invention relates to methods of evaluating transplant rejection in a host comprising determining a heightened magnitude of gene expression of genes in rejection-associated gene clusters. The disclosed gene clusters include genes that are substantially co-expressed with cytotoxic lymphocyte pro-apoptotic genes, cytoprotective genes and several other cytokine and immune cell genes.