The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2005

Filed:

Jun. 06, 1995
Applicants:

Napoleone Ferrara, Belvedere, CA (US);

Denis Gospodarowicz, San Francisco, CA (US);

Jean Plouet, Paris, FR;

Inventors:

Napoleone Ferrara, Belvedere, CA (US);

Denis Gospodarowicz, San Francisco, CA (US);

Jean Plouet, Paris, FR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K038/18 ;
U.S. Cl.
CPC ...
Abstract

A novel growth factor specific for vascular endothelial cells has been identified in conditioned medium of bovine pituitary derived folliculo stellate cells. This factor, named folliculo stellate derived growth facto (FSdGF) or vascular endothelial growth factor (VEGF), was purified to homogeneity by a combination of heparin sepharose affinity chromatography, Bio Gel P-60 exclusion chromatography, Mono S ion exchange chromatography and hydrophobic chromatography on a C4 reverse phase HPLC column. The factor is also found in the murine AtT-20 cell line.


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