The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2005

Filed:

May. 16, 2001
Applicants:

Martin Edward Fox, Histon, GB;

Mark Jackson, Cambridge, GB;

Inventors:

Martin Edward Fox, Histon, GB;

Mark Jackson, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D307/20 ;
U.S. Cl.
CPC ...
Abstract

For the preparation of an 11-oxaprostaglandin such as [2R,(1E,3R),3S,(4Z),4R)]-7-{tetrahydro-2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-4-hydroxy-3-furanyl}-4-heptenoic acid and its ester derivatives, a novel process uses a novel enantiomerically enriched compound for formula (1) wherein the bond between carbon atoms y and z is either a single or double bond; Ris selected from vinyl, trialkylsilylethynyl, a formyl group protected as an acetal, or a protected hydroxymethyl group; Ris Calkyl, optionally substituted at the terminus with an aryloxy or alkoxy group; and R-Rare independently selected from Calkyl and Caryl


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