The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2005
Filed:
May. 01, 2000
Jeffrey A. Hubbell, Zumikon, CH;
Jason C. Schense, Zurich, CH;
Shelly E. Sakiyama-elbert, Zurich, CH;
Jeffrey A. Hubbell, Zumikon, CH;
Jason C. Schense, Zurich, CH;
Shelly E. Sakiyama-Elbert, Zurich, CH;
Eidgenossische Technische Hochschule Zurich, Zurich, CH;
Universitat Zurich, Zurich, CH;
Abstract
Proteins are incorporated into protein or polysaccharide matrices for use in tissue repair, regeneration and/or remodeling, and/or drug delivery. The proteins can be incorporated so that they are released by degradation of the matrix, enzymatic action, and/or diffusion. In one embodiment, a fusion protein, which contains a crosslinking region, such as a factor XIIIa substrate, and a native protein sequence, such as a bioactive factor, is constructed. Degradable linkages may be included between the crosslinking region and the bioactive factor.