The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2005
Filed:
Apr. 27, 2000
Dara H. Lockert, Seattle, WA (US);
Carmel M. Lynch, Kenmore, WA (US);
Haim Burstein, Sammamish, WA (US);
Anthony M. Stephan, Seattle, WA (US);
Dara H. Lockert, Seattle, WA (US);
Carmel M. Lynch, Kenmore, WA (US);
Haim Burstein, Sammamish, WA (US);
Anthony M. Stephan, Seattle, WA (US);
Targeted Genetics Corporation, Seattle, WA (US);
Abstract
Isolated recombinant polynucleotides comprising elements which promote encapsidation into AAV particles, packaging cells comprising the recombinant polynucleotides, and methods for their use are provided in the present invention. These isolated recombinant polynucleotides comprise a non-AAV ITR encapsidation element (such as the P1 sequence located within the AAV S1 integration site of human chromosome 19) operably linked to one or more heterologous genes to be encapsidated. The constructs may be either integrated into a mammalian cell genome, maintained episomally, or provided transiently.