The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2005
Filed:
Feb. 18, 1999
Michael Petersen, Visp, CH;
Olwen Birch, Visp, CH;
Sakayu Shimizu, Kyoto, JP;
Andreas Kjener, Visp, CH;
Marie-luise Hischier, Visp, CH;
Susanne Thöni, Naters, CH;
Michael Petersen, Visp, CH;
Olwen Birch, Visp, CH;
Sakayu Shimizu, Kyoto, JP;
Andreas Kjener, Visp, CH;
Marie-Luise Hischier, Visp, CH;
Susanne Thöni, Naters, CH;
Lonza AG, Basel, CH;
Abstract
The invention relates to a biotechnological method for producing trifluoro-3(R)-hydroxybutyric acid derivatives of the general formula (I), where Rrepresents —OR, where Ris hydrogen, Calkyl, Calkenyl, Ccy-cloalkyl, aryl, alkoxyalkyl or alkoxyalkoxyalkyl; —NRR, where Rand Rare the same or different and represent hydrogen, Calkyl, Calkenyl, Ccycloalkyl or aryl; or —SR, where Rrepresents hydrogen, Calkyl, Calkenyl, aryl or Ccycloalkyl, based on a trifluoroacetoacetic acid derivative of the general formula (II), where Rhas the meaning given above, by means of micro-organisms which are able to reduce a carbonyl function or by means of a cell-free enzyme extract of said micro-organisms.