The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2005
Filed:
Sep. 06, 2001
Applicants:
Hakon Hakonarson, Reykjavik, IS;
Michael M. Grunstein, Merion, PA (US);
Inventors:
Hakon Hakonarson, Reykjavik, IS;
Michael M. Grunstein, Merion, PA (US);
Assignees:
deCODE genetics ehf., Reykjavik, IS;
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N033/53 ; G01N033/567 ;
U.S. Cl.
CPC ...
Abstract
The present invention relates to methods for inducing a pro-asthma/pro-inflammatory like state in a resident tissue cell, comprising contacting the cell with IL-1β, TNFα or both. Methods are also disclosed for identifying genes that regulate responses to anti-inflammatory drugs, to methods for drug screening, and to methods for identifying genes that correlate with various pro-asthma/pro-inflammatory disease phenotypes.