The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6893821 B1

PDF
Full Text
Expired
Date of Patent:
May. 17, 2005

Filed:

May. 04, 2001
Applicants:

Eyal Raz, Del Mar, CA (US);

Augusto Lois, Escondido, CA (US);

Kenji Takabayashi, San Diego, CA (US);

Inventors:

Eyal Raz, Del Mar, CA (US);

Augusto Lois, Escondido, CA (US);

Kenji Takabayashi, San Diego, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q001/68 ; C12N015/00 ; C12N015/63 ; C12N001/20 ; C07H021/04 ; C07H021/00 ; A61K038/00 ; C07K001/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for modulating cell death in a eukaryotic cell, and methods for reducing DNA damage in a eukaryotic cell. The methods generally comprise modulating a biological activity of DNA-PK in a cell. The invention further provides methods of treating a condition related to cell death in an individual. The invention further provides methods of identifying agents which modulate a biological activity of DNA-PK, as well as agents identified by the methods. Methods of modulating an immune response using an identified agent are also provided.


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