The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Jan. 11, 2001
Mark Joseph Burk, Landbeach, GB;
OM Prakash Goel, Ann Arbor, MI (US);
Marvin Simon Hoekstra, Holland, MI (US);
Thomas Frederick Mich, Ann Arbor, MI (US);
Thomas Mulhern, Hudsonville, MI (US);
James A. Ramsden, Cambridge, GB;
Mark Joseph Burk, Landbeach, GB;
Om Prakash Goel, Ann Arbor, MI (US);
Marvin Simon Hoekstra, Holland, MI (US);
Thomas Frederick Mich, Ann Arbor, MI (US);
Thomas Mulhern, Hudsonville, MI (US);
James A. Ramsden, Cambridge, GB;
Warner-Lambert Company, Morris Plains, NJ (US);
Abstract
This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.