The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2005

Filed:

Nov. 13, 2001
Applicants:

Gerald R. Crabtree, Woodside, CA (US);

Stuart L. Schreiber, Cambridge, MA (US);

David M. Spencer, Los Altos, CA (US);

Thomas J. Wandless, Cambridge, MA (US);

Peter Belshaw, Somerville, MA (US);

Inventors:

Gerald R. Crabtree, Woodside, CA (US);

Stuart L. Schreiber, Cambridge, MA (US);

David M. Spencer, Los Altos, CA (US);

Thomas J. Wandless, Cambridge, MA (US);

Peter Belshaw, Somerville, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K002/00 ; C07K004/00 ;
U.S. Cl.
CPC ...
Abstract

We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells


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