The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Apr. 23, 2003
David Boothman, Sagamore Hills, OH (US);
Jinming Gao, Pepper Pike, OH (US);
Norased Nasongkla, Cleveland, OH (US);
John Pink, Shaker Heights, OH (US);
David Boothman, Sagamore Hills, OH (US);
Jinming Gao, Pepper Pike, OH (US);
Norased Nasongkla, Cleveland, OH (US);
John Pink, Shaker Heights, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment using the subject polymer compositions, and methods of making and using the same. In another part, the present invention includes inclusion complexes of a lapachone or a prodrug thereof and a cyclodextrin, preferably a β-cyclodextrin, such as hydroxypropyl β-cyclodextrin, e.g., to improve the solubility of the lapachone or prodrug thereof.