The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2005

Filed:

Feb. 23, 2001
Applicants:

Yan Feng, Brookline, MA (US);

Tarun M. Kapoor, New York, NY (US);

Thomas Mayer, Brookline, MA (US);

Zoltan Maliga, East Brunswick, NJ (US);

Timothy J. Mitchison, Brookline, MA (US);

Justin Yarrow, Boston, MA (US);

Inventors:

Yan Feng, Brookline, MA (US);

Tarun M. Kapoor, New York, NY (US);

Thomas Mayer, Brookline, MA (US);

Zoltan Maliga, East Brunswick, NJ (US);

Timothy J. Mitchison, Brookline, MA (US);

Justin Yarrow, Boston, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/437 ; C02D471/04 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides for compounds, compositions, methods and systems for inhibiting cell growth. More specifically, the present invention provides for methods, compounds and compositions which are capable of inhibiting mitosis in metabolically active cells. Compounds, compositions and methods of the present invention inhibit the activity of a protein involved in the assembly and maintenance of the mitotic spindle. One class of proteins which acts on the mitotic spindle is the family of mitotic kinesins, a subset of the kinesin superfamily.


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