The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Oct. 25, 2002
Ivan Richards, Kalamazoo, MI (US);
Sue K. Cammarata, Portage, MI (US);
Craig D. Wegner, Mundelein, IL (US);
Michael Hawley, Kalamazoo, MI (US);
Mark Peter Warchol, Kalamazoo, MI (US);
Mark Kontny, Libertyville, IL (US);
Walter Morozowich, Kalamazoo, MI (US);
Karen Patrice Kolbasa, Schoolcraft, MI (US);
Malcolm Wilson Moon, Kalamazoo, MI (US);
Dominique Bonafoux, St. Louis, MO (US);
Sergey Gregory Wolfson, Chesterfield, MO (US);
Patrick James Lennon, Webster Groves, MO (US);
Ivan Richards, Kalamazoo, MI (US);
Sue K. Cammarata, Portage, MI (US);
Craig D. Wegner, Mundelein, IL (US);
Michael Hawley, Kalamazoo, MI (US);
Mark Peter Warchol, Kalamazoo, MI (US);
Mark Kontny, Libertyville, IL (US);
Walter Morozowich, Kalamazoo, MI (US);
Karen Patrice Kolbasa, Schoolcraft, MI (US);
Malcolm Wilson Moon, Kalamazoo, MI (US);
Dominique Bonafoux, St. Louis, MO (US);
Sergey Gregory Wolfson, Chesterfield, MO (US);
Patrick James Lennon, Webster Groves, MO (US);
Pharmacia & Upjohn Company, Peapack, NJ (US);
Abstract
Novel quaternary ammonium compounds of the formulaand any stereoisomers thereof, wherein R, Rand Rindependently represent C-Calkyl, optionally substituted with phenyl or hydroxyl, or both, and wherein any two of R, Rand Rmay form a ring together with the quaternary ammonium nitrogen; Rrepresents —H, —CH, or —CO—R, wherein Rrepresents —(C-Calkyl), —(C-Calkoxy), or —NRR, wherein Rand Rindependently represent —H or —(C-Calkyl); R, Rand Rindependently represent —H, —OCH, —OH, —CONH, —SONH, —F, —Cl, —Br, —I, —CF, or —(C-Calkyl), optionally substituted with one or two —OH, —(C-Calkoxy), —COOH, or —CO—O—(C-Calkyl); and Xrepresents an anion of a pharmaceutically acceptable acid, the compounds for use as medicaments, use of the compounds for the manufacture of specific medicaments, and pharmaceutical compositions comprising the compounds. The present invention also concerns a method of treatment involving administration of the compounds.