The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Aug. 09, 2002
Hans-ulrich Demuth, Halle/Saale, DE;
Konrad Glund, Halle/Saale, DE;
Andrew J. Pospisilik, West Vancouver, CA;
Kerstin Kuehn-wache, Halle/Saale, DE;
Hans-Ulrich Demuth, Halle/Saale, DE;
Konrad Glund, Halle/Saale, DE;
Andrew J. Pospisilik, West Vancouver, CA;
Kerstin Kuehn-Wache, Halle/Saale, DE;
Prosidion Limited, Oxford, GB;
Abstract
The present invention discloses methods for therapeutically treating mammals, including but not limited to humans, to increase the relative insulin producing performance of endogenous pancreatic β-cells, to cause differentiation of pancreatic epithelial cells into insulin producing β-cells, to improve muscle sensitivity to insulin and other weight control efforts by the chronic oral administration of a DP IV-inhibitor. The administration causes the active form of GLP-1 and other non-nutrient stimulated growth hormones to remain biologically active longer under physiological conditions. The extended presence of such hormones, in particular in the pancreatic tissue can also facilitate differentiation and regeneration of the β-cells already present that are in need of repair.