The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Sep. 01, 1997
Guy Serre, Toulouse, FR;
Elisabeth Girbal-neuhauser, Toulouse, FR;
Christian Vincent, Lauzerville, FR;
Michel Simon, Escalquens, FR;
Mireille Sebbag, Toulouse, FR;
Pascal Dalbon, Lyons, FR;
Colette Jolivet-reynaud, Bron, FR;
Michel Arnaud, Villeurbane, FR;
Michel Jolivet, Bron, FR;
Guy Serre, Toulouse, FR;
Elisabeth Girbal-Neuhauser, Toulouse, FR;
Christian Vincent, Lauzerville, FR;
Michel Simon, Escalquens, FR;
Mireille Sebbag, Toulouse, FR;
Pascal Dalbon, Lyons, FR;
Colette Jolivet-Reynaud, Bron, FR;
Michel Arnaud, Villeurbane, FR;
Michel Jolivet, Bron, FR;
Biomerieux, Marcy-L'Etoile, FR;
Abstract
The invention concerns an artificial antigen specifically identified by the anti-filaggrin autoantibodies present in the serum of patients suffering from rheumatoid polyarthritis, and consisting of one polypeptide comprising all or part of the sequence of one filaggrin unit or of a related molecule, in which an arginine radical has been substituted by a citrulline radical. The invention also concerns the use of this antigen for diagnosing rheumatoid polyarthritis.