The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
Aug. 15, 2000
Yoav Blatt, Rehovot, IL;
Oded Arad, Rehovot, IL;
Eugene Kimelman, Tel Aviv, IL;
David Cohen, Petach Tikva, IL;
Rika Pinto, Tel-Aviv, IL;
Avner Rotman, Rehovot, IL;
Yoav Blatt, Rehovot, IL;
Oded Arad, Rehovot, IL;
Eugene Kimelman, Tel Aviv, IL;
David Cohen, Petach Tikva, IL;
Rika Pinto, Tel-Aviv, IL;
Avner Rotman, Rehovot, IL;
Bio Dar Ltd., Yavne, IL;
Abstract
There is provided an orally-administrable formulation for the controlled release or stable storage of a granulated isoflavone-enriched fraction or mixture of such fractions, comprising at least one granulated isoflavone-enriched fraction and at least one carrier, diluent or excipient therefor. Preferably, the formulation is characterized in that the total in vitro dissolution time of said formulation required for release of 75% of the active ingredients available from the formulation is between about 4 and about 18 hours, as determined by the U.S.P. XXIII paddle method at a paddle speed of 75 rpm, using simulated intestinal fluid without the digestive enzymes normally found in intestinal fluid, at pH 6.8, and a temperature of 37° C. A process for the preparation of such a formulation is also provided.