The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2005
Filed:
Jan. 11, 2002
Olivier Lavergne, Palaiseau, FR;
Christophe Lanco, Dourdan, FR;
Grégoire Prevost, Antony, FR;
Beng Poon Teng, Gif-sur-Yvette, FR;
Olivier Lavergne, Palaiseau, FR;
Christophe Lanco, Dourdan, FR;
Grégoire Prevost, Antony, FR;
Beng Poon Teng, Gif-sur-Yvette, FR;
Abstract
The invention concerns novel mikanolide derivatives, their preparation method and their therapeutic uses, in particular as anti-cancer and anti-viral agents. The compounds correspond to general formula (1) corresponding to general sub-formulae (I)and (I), wherein: Rrepresents H, SRor NRR; Rrepresents SRor NRR; Rrepresents OH, O(CO)R, OSiRRR, O(CO)ORor O(CO)NHR, each of the radicals R, R, R, Rand Rrepresenting independently (in particular) an alkyl radical, the radicals Rand Rrepresenting (in particular) radicals selected independently among a hydrogen atom and an alkyl radical, and each of the radicals Rand Rrepresenting independently (in particular) an alkyl or cycloalkyl radical, or one among aryl, heteroaryl, aralkyl or heteroalkyl radicals optionally substituted; provided that when the compounds correspond to the general sub-formula (I), then Rdoes not represent a hydrogen atom