The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2005

Filed:

Mar. 06, 2003
Applicants:

Walter-gunar Friebe, Mannheim, DE;

Birgit Masjost, Munich, DE;

Ralf Schumacher, Penzberg, DE;

Inventors:

Walter-Gunar Friebe, Mannheim, DE;

Birgit Masjost, Munich, DE;

Ralf Schumacher, Penzberg, DE;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D401/00 ; C07D405/00 ; C07D409/00 ; C07D403/00 ; A61K031/55 ;
U.S. Cl.
CPC ...
Abstract

This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula (I)wherein the symbols are defined in the specification, as well as processes for their manufacture. The compounds according to this invention possess anti-cell proliferation activity and show an increased plasma-stability.


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