The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2005
Filed:
Aug. 06, 2004
Sang Hoon Paik, Yongin-si, KR;
Yong Nam Shin, Wonju-si, KR;
Jean Man Kim, Yongin-si, KR;
Jae Wook Huh, Yongin-si, KR;
Jung Sik Lee, Yongin-si, KR;
Ki Sung Kwon, Gwacheon-si, KR;
Ji Hyun Chun, Yongin-si, KR;
Sang Hoon Paik, Yongin-si, KR;
Yong Nam Shin, Wonju-si, KR;
Jean Man Kim, Yongin-si, KR;
Jae Wook Huh, Yongin-si, KR;
Jung Sik Lee, Yongin-si, KR;
Ki Sung Kwon, Gwacheon-si, KR;
Ji Hyun Chun, Yongin-si, KR;
Korea Green Cross Corporation, Yongin-si, KR;
Abstract
Disclosed is a lyophilized preparation of recombinant factor VIII used as a therapeutic preparation of hemophilia A. The lyophilized preparation of recombinant factor VIII is prepared by performing lyophilization using a mixture comprising 6 to 100 mM of L-arginine, 3.5 to 50 mM of L-isoleucine, and 10 to 100 mM of L-glutamic acid as a stabilizer for stabilizing the recombinant factor VIII which exhibits an unstable activity during lyophilization, rather than using human blood derived albumin.