The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2005

Filed:

Nov. 10, 2000
Applicants:

Eugene Rosenberg, Givat Shmuel, IL;

Eliora Ron, Tel Aviv, IL;

Elisha Orr, Leicester, GB;

Yossi Paitan, Rishon Le-Zion, IL;

Inventors:

Eugene Rosenberg, Givat Shmuel, IL;

Eliora Ron, Tel Aviv, IL;

Elisha Orr, Leicester, GB;

Yossi Paitan, Rishon Le-Zion, IL;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N009/00 ;
U.S. Cl.
CPC ...
Abstract

There is provided DNA sequences isolated frompartially encoding a functional portion of a polypeptide component required for the synthesis of antibiotic TA. Also provided are purified, isolated and cloned DNA sequences encoding a polypeptide component required for postmodification of antibiotic TA and encoding a gene product involved in the regulation of the biosynthesis of antibiotic TA. A purified, isolated and cloned DNA sequence having a DNA sequence (seq. ID No:2 and 20) encoding a polypeptide component required for encoding the TA gene cluster and any mutations thereof is provided. Also provided are methods of using the TA genes for combinatorial genetics and of using the TA genes encoding for synthesis and modification or regulation of antibiotic TA.


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