The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2005

Filed:

Dec. 06, 1999
Applicants:

Peter S. Linsley, Seattle, WA (US);

Jeffrey A. Ledbetter, Seattle, WA (US);

Nitin K. Damle, Monmont Junction, NJ (US);

William Brady, Bothell, WA (US);

Inventors:

Peter S. Linsley, Seattle, WA (US);

Jeffrey A. Ledbetter, Seattle, WA (US);

Nitin K. Damle, Monmont Junction, NJ (US);

William Brady, Bothell, WA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K038/17 ; C07K014/705 ; C12N015/12 ; C12N015/63 ;
U.S. Cl.
CPC ...
Abstract

This invention provides methods for regulating T cell interactions with B7 positive cells. Methods are provided for using B7 antigen, its fragments and derivatives reactive with CTLA4 receptor, to regulate CTLA4 positive T cell responses, and immune responses mediated by T cells.


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