The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2005

Filed:

Apr. 04, 2001
Applicants:

Carmelita G. Frondoza, Woodstock, MD (US);

David J. Fink, Baltimore, MD (US);

David S. Hungerford, Cockeysville, MD (US);

Alan H. Shikani, Ruxton, MD (US);

Inventors:

Carmelita G. Frondoza, Woodstock, MD (US);

David J. Fink, Baltimore, MD (US);

David S. Hungerford, Cockeysville, MD (US);

Alan H. Shikani, Ruxton, MD (US);

Assignees:

The Johns Hopkins University, Baltimore, MD (US);

Chrondros, Inc., Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B019/00 ;
U.S. Cl.
CPC ...
Abstract

Disclosed is a method of growing cells on biodegradable microcarrier particles and more specifically growing chondrocytes for an extended period of time until they aggregate. These aggregated cells can be injected directly or shaped for implantation into the body. In another embodiment of this invention, the cell microcarrier aggregates are grown in a mold that is shaped to conform to the geometry of the desired body part to be replaced. An apparatus for shaping the aggregated cells is disclosed. The aggregated cells can be supplied in a kit.


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