The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2005

Filed:

Sep. 29, 2000
Applicants:

Masanobu Shinoda, Ibaraki, JP;

Eita Emori, Ibaraki, JP;

Fumiyoshi Matsuura, Ibaraki, JP;

Toshihiko Kaneko, Ibaraki, JP;

Norihito Ohi, Ibaraki, JP;

Shunji Kasai, Ibaraki, JP;

Hideki Yoshitomi, Ibaraki, JP;

Kazuto Yamazaki, Ibaraki, JP;

Sadakazu Miyashita, Ibaraki, JP;

Taro Hibara, Ibaraki, JP;

Takashi Seiki, Ibaraki, JP;

Richard Clark, Ibaraki, JP;

Hitoshi Harada, Ibaraki, JP;

Inventors:

Masanobu Shinoda, Ibaraki, JP;

Eita Emori, Ibaraki, JP;

Fumiyoshi Matsuura, Ibaraki, JP;

Toshihiko Kaneko, Ibaraki, JP;

Norihito Ohi, Ibaraki, JP;

Shunji Kasai, Ibaraki, JP;

Hideki Yoshitomi, Ibaraki, JP;

Kazuto Yamazaki, Ibaraki, JP;

Sadakazu Miyashita, Ibaraki, JP;

Taro Hibara, Ibaraki, JP;

Takashi Seiki, Ibaraki, JP;

Richard Clark, Ibaraki, JP;

Hitoshi Harada, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/192 ; C07C059/64 ;
U.S. Cl.
CPC ...
Abstract

Novel carboxylic acid derivatives of general formula (I), salts of the same, esters thereof, or hydrates of them, which are useful as insulin resistance improvers; and drugs containing the derivatives as the active ingredient. In said formula, Ris hydrogen, hydroxyl, alkyl, or the like; L is a single bond, a double bond, alkylene, or the like; M is a single bond, alkylene, or the like; T is a single bond, alkylene, or the like; W is carboxyl, —CON(R)R, or the like;represents a single or double bond; X is oxygen, alkenylene, or the like; Y is an aromatic hydrocarbon group which may contain a heteroatom, or the like; and Z is an aromatic hydrocarbon group which may contain a heteroatom.


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