The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2005
Filed:
Sep. 18, 2002
Masaaki Nagasawa, Saitama, JP;
Hiroyasu Nishioka, Saitama, JP;
Kazuyasu Asami, Saitama, JP;
Naoyoshi Miura, Saitama, JP;
Yutaka Shinozaki, Saitama, JP;
Hitoshi Morita, Saitama, JP;
Masaaki Nagasawa, Saitama, JP;
Hiroyasu Nishioka, Saitama, JP;
Kazuyasu Asami, Saitama, JP;
Naoyoshi Miura, Saitama, JP;
Yutaka Shinozaki, Saitama, JP;
Hitoshi Morita, Saitama, JP;
Zeria Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A benzimidazole derivative of formula (1):(wherein R represents a hydrogen atom or a methoxy group, and n is 0 or 1) or a salt thereof; and a medicament containing the same. The compounds of the present invention, due to minimized difference in therapeutic effect between subjects, which difference would otherwise be derived from different CYP2C19 activity from subject to subject, ensure that all patients can enjoy proper therapeutic effects at the same dose of the drug. Also, the compounds of the invention have low risk of drug interaction caused by induction of CYP1A family member enzymes, as well as low risk of development of cancer, and thus is useful as a remedy for peptic ulcer, reliably providing therapeutic effects with safety.