The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2005
Filed:
May. 18, 1998
Petrus Hendricus Nibbering, Voorhout, NL;
Pieter Sicco Hiemstra, Leiderdorp, NL;
Maria Theodora Van Den Barselaar, Wassenaar, NL;
Ernest Karel Jacob Pauwels, Leiden, NL;
Rolf Ide Johannes Feitsma, Leiden, NL;
Petrus Hendricus Nibbering, Voorhout, NL;
Pieter Sicco Hiemstra, Leiderdorp, NL;
Maria Theodora Van Den Barselaar, Wassenaar, NL;
Ernest Karel Jacob Pauwels, Leiden, NL;
Rolf Ide Johannes Feitsma, Leiden, NL;
RijksUniversiteit Leiden, , NL;
Abstract
The invention relates to the use of ubiquicidine or optionally modified peptide fragments derived therefrom for the preparation of a drug for the treatment, diagnostics or prophylaxis of infections in humans and animals. A peptide fragment derived from ubiquicidine comprises for instance a preferably continuous series of at least 3, preferably at least 7-13 amino acids from the amino acid sequence of ubiquicidine; KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPN ANS (SEQ ID NO: 1). Hybrid molecules comprise for instance a cationic peptide with an antimicrobial action and/or a peptide fragment of ubiquicidine and/or a derivative thereof and one or more effector molecules.