The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2005
Filed:
Oct. 06, 1999
Peter G. Zaphiropoulos, Tullinge, SE;
Anne Birgitte Unden, Djursholm, SE;
Rune Toftgård, Skärholmen, SE;
Fahimeh Rahnama, Stockholm, SE;
Robert E. Hollingsworth, Research Triangle Park, NC (US);
Peter G. Zaphiropoulos, Tullinge, SE;
Anne Birgitte Unden, Djursholm, SE;
Rune Toftgård, Skärholmen, SE;
Fahimeh Rahnama, Stockholm, SE;
Robert E. Hollingsworth, Research Triangle Park, NC (US);
Karolinska Innovations AB, Stockholm, SE;
Pharmacia & Upjohn Company, Kalamazoo, MI (US);
Abstract
The present invention relates to a novel human patched-like gene (PTCH2), which for the first time has been cloned and sequenced. Several alternatively spliced mRNA forms of PTCH2 have been identified, including transcripts lacking segments thought to be involved in sonic hedgehog (SHH) binding and mRNAs with differentially defined 3' terminal exons. Further, the invention also relates to the protein encoded by the present PTCH2 as well as to functional analogues and variants thereof.