The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2005

Filed:

Aug. 31, 2000
Applicants:

Paul D. Robbins, Mt. Lebanon, PA (US);

Zhibao MI, Pittsburgh, PA (US);

Raymond Frizzell, Pittsburgh, PA (US);

Joseph C. Glorioso, Cheswick, PA (US);

Andrea Gambotto, Pittsburgh, PA (US);

Inventors:

Paul D. Robbins, Mt. Lebanon, PA (US);

Zhibao Mi, Pittsburgh, PA (US);

Raymond Frizzell, Pittsburgh, PA (US);

Joseph C. Glorioso, Cheswick, PA (US);

Andrea Gambotto, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K038/04 ; C12P021/08 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to internalizing peptides which facilitate the uptake and transport of cargo into the cytoplasm and nuclei of cells as well as methods for the identification of the peptides, and methods of use for the peptides. The internalizing peptides of the present invention are selected for their ability to efficiently internalize cargo into a wide variety of cell types both in vivo and in vitro.


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