The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2005
Filed:
Oct. 20, 2000
Applicants:
David J. Fitzgerald, Rockville, MD (US);
Michael J. Iadarola, Washington, DC (US);
Inventors:
David J. FitzGerald, Rockville, MD (US);
Michael J. Iadarola, Washington, DC (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K001/36 ; C07K002/00 ; A61K038/00 ;
U.S. Cl.
CPC ...
Abstract
The invention pertains to the discovery of novel disulfide linked cell toxins which can ablate NK-1 receptor expressing cells. These toxins are used as pharmaceutical compositions for the ablation of NK1 receptor expressing cells and comprise a substance P (SP)-exotoxin disulfide linked conjugate. The invention also includes methods of making and using these toxins and pharmaceutical compositions.