The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6881420 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 19, 2005

Filed:

Dec. 20, 2001
Applicants:

Moshe Flashner-barak, Petach Tikva, IL;

Vered Rosenberger, Jerusalem, IL;

E. Itzhak Lerner, Petach Tikva, IL;

Inventors:

Moshe Flashner-Barak, Petach Tikva, IL;

Vered Rosenberger, Jerusalem, IL;

E. Itzhak Lerner, Petach Tikva, IL;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K009/20 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides oral dosage forms and compositions for administering antineoplastic agents, such as irinotecan, etoposide, paclitaxel, doxorubicin and vincristine, whose oral effectiveness is limited by pre-systemic and systemic deactivation in the GI tract. Gelling of the gastric retention vehicle composition, and in the case of solid forms concomitant expansion of the composition, retains the antineoplastic drug in the patient's stomach, minimizing pre-systemic and/or systemic deactivation of the drug.


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