The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2005
Filed:
Feb. 15, 1999
Sarkis Barret Kalindjian, Banstead Surrey, GB;
Ildiko Maria Buck, London, GB;
Ian Duncan Linney, Guildford, GB;
Gillian Fairfull Watt, West Croydon, GB;
Elaine Anne Harper, Beds, GB;
Nigel Paul Shankley, Tonbridge, GB;
Sarkis Barret Kalindjian, Banstead Surrey, GB;
Ildiko Maria Buck, London, GB;
Ian Duncan Linney, Guildford, GB;
Gillian Fairfull Watt, West Croydon, GB;
Elaine Anne Harper, Beds, GB;
Nigel Paul Shankley, Tonbridge, GB;
James Black Foundation Limited, London, GB;
Abstract
Compounds of formula (I) (and pharmaceutically acceptable salts thereof) are histamine Hreceptor ligands. A in the formula represents (CH), m being from 1 to 3; B is (CH), n being from 1 to 3; x is from 0 to 2; Ris Cto Chydrocarbyl, in which up to 2 carbon atoms may be replaced by O, S or N; and up to 2 hydrogen atoms may be replaced by halogen; Ris H or Cto Chydrocarbyl, in which up to 3 carbon atoms may be replaced by O, S or N, and up to 3 hydrogen atoms may be replaced by halogen; Ris absent when —Y—Z—Ris attached to W, or is H or Cto Chydrocarbyl when —Y—Z—Ris not attached to W; W is nitrogen; X is —CH—, —O— or —NR—, Rbeing H or Cto Calkyl; Y replaces a hydrogen atom on any of A, B, W and X, and is Cto Calkylene, in which one non-terminal carbon atom may be replaced by O; and Z is (II), (III), (IV), (V), (VI), or (VII) wherein R, Rand Rare independently H or Cto Chydrocarbyl, in which up to 3 carbon atoms may be replaced by O or N, and up to 3 hydrogen atoms may be replaced by halogen, and Q is H or methyl, or Q is linked to Ror Rto form a five-membered ring or Q is linked to Rto form a six-membered ring