The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2005

Filed:

Jul. 17, 2002
Applicants:

Benny Askew, Newbury Park, CA (US);

Jeffrey Adams, Thousand Oaks, CA (US);

Shon Booker, Thousand Oaks, CA (US);

Guoqing Chen, Thousand Oaks, CA (US);

Lucian V. Dipietro, Gloucester, MA (US);

Daniel Elbaum, Newton, MA (US);

Julie Germain, Medford, MA (US);

Stephanie D. Geuns-meyer, Medford, MA (US);

Gregory J. Habgood, Merrimac, MA (US);

Michael Handley, Greenbrae, CA (US);

Qi Huang, Moorpark, CA (US);

Tae-seong Kim, Thousand Oaks, CA (US);

Aiwen LI, Westlake Village, CA (US);

Nobuko Nishimura, West Hills, CA (US);

Rana Nomak, Istanbul, TR;

Vinod F. Patel, Acton, MA (US);

Babak Riahi, Woodland Hills, CA (US);

Joseph L. Kim, Wayland, MA (US);

Ning Xi, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Chester Chenguang Yuan, Newbury Park, CA (US);

Inventors:

Benny Askew, Newbury Park, CA (US);

Jeffrey Adams, Thousand Oaks, CA (US);

Shon Booker, Thousand Oaks, CA (US);

Guoqing Chen, Thousand Oaks, CA (US);

Lucian V. DiPietro, Gloucester, MA (US);

Daniel Elbaum, Newton, MA (US);

Julie Germain, Medford, MA (US);

Stephanie D. Geuns-Meyer, Medford, MA (US);

Gregory J. Habgood, Merrimac, MA (US);

Michael Handley, Greenbrae, CA (US);

Qi Huang, Moorpark, CA (US);

Tae-Seong Kim, Thousand Oaks, CA (US);

Aiwen Li, Westlake Village, CA (US);

Nobuko Nishimura, West Hills, CA (US);

Rana Nomak, Istanbul, TR;

Vinod F. Patel, Acton, MA (US);

Babak Riahi, Woodland Hills, CA (US);

Joseph L. Kim, Wayland, MA (US);

Ning Xi, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Chester Chenguang Yuan, Newbury Park, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/4427 ; C07D401/12 ;
U.S. Cl.
CPC ...
Abstract

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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