The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 05, 2005

Filed:

Jan. 31, 2002
Applicants:

Saul Brusilow, Baltimore, MD (US);

Richard J. Traystman, Ruxton, MD (US);

Raymond C. Koehler, Baltimore, MD (US);

Inventors:

Saul Brusilow, Baltimore, MD (US);

Richard J. Traystman, Ruxton, MD (US);

Raymond C. Koehler, Baltimore, MD (US);

Assignee:

MSO Pharma LLC, Chevy Chase, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/198 ;
U.S. Cl.
CPC ...
Abstract

Methods for the treatment of both diseases susceptible to the inhibition of mammalian glutamine synthetase and progressive hyperammonemic encephalopathy comprising administering L-methionine S-sulfoxime at a dose not to exceed 10 mg/kg body weight are disclosed. Preferably, the dose should not exceed 8 mg/kg; more preferably, the dose should not exceed 5 mg/kg; most preferably, the dose should not exceed 2.5 mg/kg.


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