The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2005
Filed:
Dec. 01, 2000
Constant Adriaan Anton Van Boeckel, Oss, NL;
Cornelis Maria Tromp, Ravenstein, NL;
Tamara Theodora Maria Geertsen, Westervoort, NL;
Constant Adriaan Anton Van Boeckel, Oss, NL;
Cornelis Maria Tromp, Ravenstein, NL;
Tamara Theodora Maria Geertsen, Westervoort, NL;
Akzo Nobel N.V., Arnhem, NL;
Abstract
The present invention relates to compounds of the formula (I), wherein R is independently SOor CH; the spacer is a flexible spacer of a length of 13-25 atoms; the charge of the pentasaccharide residue is compensated by positively charged counterions; and the total number of sulfate groups in the pentasaccharide residue is 4, 5 or 6; or a pharmaceutically acceptable salt, a prodrug or a solvate thereof. The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombin-related diseases.