The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2005
Filed:
Jan. 22, 2003
Applicants:
Kuo-hsiung Lee, Chapel Hill, NC (US);
Zhiyan Xiao, Chapel Hill, NC (US);
Kenneth F. Bastow, Chapel Hill, NC (US);
Inventors:
Kuo-Hsiung Lee, Chapel Hill, NC (US);
Zhiyan Xiao, Chapel Hill, NC (US);
Kenneth F. Bastow, Chapel Hill, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D317/70 ;
U.S. Cl.
CPC ...
Abstract
Etoposide analogs such as 4'-O-demethyl-4β-[4″-(methyl-L-tyrosine-N-carbonyl)-anilino]-4-desoxy-podophyllotoxin (12) and 4′-O-demethyl-4β-[4″-(methyl-L-tryptophan-N-carbonyl)-anilino]-4-desoxypodophyllotoxin (13) are described, along with pharmaceutical formulations containing the same, methods of use thereof, and intermediates and methods of making the same.