The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2005
Filed:
Jul. 16, 2003
Julien Alistair Brown, Reading, GB;
Stuart Bailey, Dorking, GB;
Stephen Brand, Reading, GB;
Celltech R & D Limited, , GB;
Abstract
Phenylalanine enamide derivatives of formula (1) are described:wherein Ris a —CH, —(CH)CH, —CHCHOH, —CHCHOCH, —CHCHOCHCHOH, —CHCHOCHCHOCH,group;and the salts, solvates and N-oxides thereof. Compounds according to the invention are potent and selective inhibitors of α4 integrins. The compounds are of use in modulating cell adhesion and in particular are of use in the prophylaxis and treatment of diseases or disorders including inflammation in which the extravasation of leukocytes plays a role and the invention extends to such a use and to the use of the compounds for the manufacture of a medicament for treating such diseases or disorders.