The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2005
Filed:
Nov. 06, 2001
Applicant:
Victor Raso, Brighton, MA (US);
Inventor:
Victor Raso, Brighton, MA (US);
Assignee:
Boston Biomedical Research Institute, Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N009/00 ; C07K016/18 ;
U.S. Cl.
CPC ...
Abstract
Disclosed are bispecific antibodies comprising a first antibody binding specificity which confers the ability of the bispecific antibody to cross the blood-brain barrier, and a second antibody specificity conferring the ability of the bispecific antibody to bind to a β-amyloid epitope. Also disclosed are methods for inhibiting the formation of β-amyloid plaques in the brain of a human, of promoting the disaggregation of a preformed β-amyloid plaque. Such methods recite the administration of a bispecific antibody.