The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2005

Filed:

Jun. 28, 2002
Applicants:

Clarence N. Ahlem, La Jolla, CA (US);

Robert J. Kaiser, Bothell, WA (US);

Kevin P. Lund, Lynnwood, WA (US);

Mark L. Stolowitz, Woodinville, WA (US);

Inventors:

Clarence N. Ahlem, La Jolla, CA (US);

Robert J. Kaiser, Bothell, WA (US);

Kevin P. Lund, Lynnwood, WA (US);

Mark L. Stolowitz, Woodinville, WA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C229/38 ; C07C255/00 ;
U.S. Cl.
CPC ...
Abstract

A reagent having the general formula of General Formula I:wherein group R is an electrophilic or a nucleophilic moiety suitable for reaction of the reagent with a biologically active species; group Ris one of H and OH moieties; group Ris one of an alkyl and a methylene bearing an electronegative substituent; group Z is one of (CH)and CHO(CHCHO), and n is an integer of from 1 to 5, and nis an integer of from 1 to 4; and each of group Zand Zare (CH)CONH(CH)CONH(CH). Also, a reagent having the general formula of General Formula II:group Ris one of H and OH moieties; group Z is one of (CH)and CHO(CHCHO), and n is an integer of from 1 to 5, and nis an integer of from 1 to 4; each of group Zand group Zinclude one of (CH)CONH(CH)CONH(CH); and (CH)CONH(CH); and group R is an electrophilic or a nucleophilic moiety suitable for reaction of the reagent with the biologically active species.


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