The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2005

Filed:

Jan. 10, 2001
Applicants:

Jörg Kleiber, Penzberg, DE;

Thomas Walter, Bichl, DE;

Herbert Harttig, Altrip, DE;

Christoph Lesniak, Saarbrücken, DE;

Martin Mennig, Quierschied, DE;

Michael Riedling, Saarbrücken, DE;

Helmut Schmidt, Saarbrücken, DE;

Inventors:

Jörg Kleiber, Penzberg, DE;

Thomas Walter, Bichl, DE;

Herbert Harttig, Altrip, DE;

Christoph Lesniak, Saarbrücken, DE;

Martin Mennig, Quierschied, DE;

Michael Riedling, Saarbrücken, DE;

Helmut Schmidt, Saarbrücken, DE;

Assignee:

Roche Diagnostics GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N015/00 ; C12N013/00 ; C12P019/34 ; C07H021/00 ;
U.S. Cl.
CPC ...
Abstract

Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free class surface or having pores with a diameter offices than 10 nm. The particles are used for separating biological material such as nucleic acids. A preferred process of preparing the particles is by forming a mixture of magnetic cores with a sol formed from an alcohol and a metal alkoxide, spray-drying the mixture to coat the cores with a layer of gelled sol, and heating the coated cores to obtain the magnetic glass particles. Preferably, the particles have an average particle size of less than 100 μm. The magnetic core may be a composite material containing a mica core and magnetite particles immobilized on the mica core, and the glass layer may contain boron oxide. Magnetic core materials include magnetite (FeO) and FeO.


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