The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2005
Filed:
Dec. 22, 1999
Noritsugu Yamasaki, Himeji, JP;
Takafumi Imoto, Arai, JP;
Takahiro Hiramura, Tsukuba, JP;
Miho Kawauchi, Tsukuba, JP;
Noriko Oku, Takatsuki, JP;
Chikako Oku, Takatsuki, JP;
Tomohito Oku, Takatsuki, JP;
Hiroshi Kayakiri, Suita, JP;
Hitoshi Sawada, Tsukuba, JP;
Noritsugu Yamasaki, Himeji, JP;
Takafumi Imoto, Arai, JP;
Takahiro Hiramura, Tsukuba, JP;
Miho Kawauchi, Tsukuba, JP;
Noriko Oku, Takatsuki, JP;
Chikako Oku, Takatsuki, JP;
Tomohito Oku, Takatsuki, JP;
Hiroshi Kayakiri, Suita, JP;
Hitoshi Sawada, Tsukuba, JP;
Fujisawa Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention provides novel benzimidazole derivatives of the following formula (I) and salts thereof:wherein Rrepresents a lower alkyl group or a lower alkyloxy-lower alkyl group; Rrepresents a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atoms, an aryl group, and such; Rrepresents a lower alkyl group, a lower alkenyl group, an aryl group, a lower alkylaryl group, an aryl-lower alkenyl group, a halothienyl group, a lower alkylamino group, or an aryl-lower alkylamino group; A represents a benzene ring, a naphthalene ring, or a pyridine ring; and X represents a halogen atom. The derivatives and their salts have blood sugar level-depressing activity or PDE5-inhibiting activity, and are useful as pharmaceutical preparations.