The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2005

Filed:

Dec. 16, 1999
Applicants:

Ning Zhang, Alameda, CA (US);

Anthony F. Purchio, Alameda, CA (US);

Inventors:

Ning Zhang, Alameda, CA (US);

Anthony F. Purchio, Alameda, CA (US);

Assignee:

Xenogen Corporation, Alameda, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K067/027 ; C12N015/63 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel promoters, including transcription regulator regions, for the mouse VEGFR-2 receptor, isolated polynucleotides comprising such promoters, nucleic acid constructs comprising such promoters operatively linked to genes encoding a gene product, such as, a reporter, a protein, polypeptide, hormone, ribozyme, or antisense RNA, recombinant cells comprising such nucleic acid constructs, screening for therapeutic drugs using such cells (e.g., screening for compounds that modulate VEGFR-2-mediated angiogenesis), and endothelial tissue-specific gene expression using these novel promoter sequences.


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