The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Oct. 03, 2001
Kenneth L. Rinehart, Urbana, IL (US);
Jose J. Morales, Urbana, IL (US);
Joel Reid, Rochester, MN (US);
Isabel Reymundo, Madrid, ES;
Pablo Floriano, Madrid, ES;
Lola Garcia Gravalos, Madrid, ES;
Kenneth L. Rinehart, Urbana, IL (US);
Jose J. Morales, Urbana, IL (US);
Joel Reid, Rochester, MN (US);
Isabel Reymundo, Madrid, ES;
Pablo Floriano, Madrid, ES;
Lola Garcia Gravalos, Madrid, ES;
Pharma Mar, S.A., Madrid, ES;
Abstract
The purification and structure elucidation of several products of the metabolism of Et 743 by human cytochrome CYP3A4 have been accomplished. These compounds are abbreviated herein as 'ETM' followed by a numeric value which represents the approximate molecular weight. Three compounds have been identified to date, namely ETM 305, ETM 775 and ETM 204. The structures of these ecteinascidin metabolites are as follows: