The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Nov. 12, 1999
Applicants:
Yogesh S. Sanghvi, Encinitas, CA (US);
Muthiah Manoharan, Carlsbad, CA (US);
Inventors:
Yogesh S. Sanghvi, Encinitas, CA (US);
Muthiah Manoharan, Carlsbad, CA (US);
Assignee:
ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/04 ; C07H021/00 ;
U.S. Cl.
CPC ...
Abstract
Novel chiral compounds that mimic and/or modulate the activity of wild-type nucleic acids are disclosed. In general, the compounds are phosphorothioate oligonucleotides wherein the 5', and the 3′-terminal internucleoside linkages are chirally Sp and internal internucleoside linkages are chirally Rp.