The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Jul. 23, 2001
Catherine Taylor, Waterloo, CA;
Tzann-wei Wang, Waterloo, CA;
Larry Petrov, Kitchener, CA;
John C. Carlson, Waterloo, CA;
Richard Narayansingh, Kitchner, CA;
John E. Thompson, Waterloo, CA;
Catherine Taylor, Waterloo, CA;
Tzann-Wei Wang, Waterloo, CA;
Larry Petrov, Kitchener, CA;
John C. Carlson, Waterloo, CA;
Richard Narayansingh, Kitchner, CA;
John E. Thompson, Waterloo, CA;
Senesco Technologies, Inc., New Brunswick, NJ (US);
Abstract
Genes encoding an apoptosis-induced eukaryotic initiation Factor-5A (eIF-5A) and an apoptosis-induced deoxyhypusine synthase (DHS), whose expressions are induced by the onset of apoptosis, are identified. The DHS gene and the eIF-5A gene, alone or in combination, as well as inhibitors of the DHS reaction, are used to modulate apoptosis in animals and humans. For example, modulation of apoptosis in cells of animals and humans is achieved by introduction of a gene or gene fragment encoding apoptosis-induced eIF-5A, apoptosis-induced DHS, or both into the animal or human cell in antisense orientation.