The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2005

Filed:

Mar. 12, 2001
Applicants:

Derk J. Hogenkamp, Carlsbad, CA (US);

Phong Nguyen, Placentia, CA (US);

Bin Shao, Richboro, PA (US);

Inventors:

Derk J. Hogenkamp, Carlsbad, CA (US);

Phong Nguyen, Placentia, CA (US);

Bin Shao, Richboro, PA (US);

Assignee:

Euro-Celtique S.A., Luxembourg, LU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D239/46 ; C07D239/48 ; A61K031/505 ; A61K031/506 ; A61P025/08 ;
U.S. Cl.
CPC ...
Abstract

This invention relates aryl substituted pyridines, pyrimidines, pyrazines and triazines of Formula I:or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A, A, A, R-R, X and Y are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.


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