The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2005

Filed:

Nov. 23, 1999
Applicants:

Robert E. Davis, San Diego, CA (US);

Soumitra S. Ghosh, San Diego, CA (US);

John S. Kiely, San Diego, CA (US);

Inventors:

Robert E. Davis, San Diego, CA (US);

Soumitra S. Ghosh, San Diego, CA (US);

John S. Kiely, San Diego, CA (US);

Assignee:

Mitokor, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K048/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to genetic mutations in mitochondrial cytochrome c oxidase genes that segregate with Alzheimer's disease (AD). The invention provides methods for detecting such mutations, as a diagnostic for Alzheimer's Disease, either before or after the onset of clinical symptoms. The invention further provides treatment of cytochrome c oxidase dysfunction.


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