The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Sep. 05, 2002
Richard Soltero, Holly Springs, NC (US);
Balasingam Radhakrishan, Chapel Hill, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Bruce Rehlaender, Chapel Hill, NC (US);
Anthony Hickey, Chapel Hill, NC (US);
LI LI Bovet, Chapel Hill, NC (US);
Richard Soltero, Holly Springs, NC (US);
Balasingam Radhakrishan, Chapel Hill, NC (US);
Nnochiri N. Ekwuribe, Cary, NC (US);
Bruce Rehlaender, Chapel Hill, NC (US);
Anthony Hickey, Chapel Hill, NC (US);
Li Li Bovet, Chapel Hill, NC (US);
Nobex Corporation, Durham, NC (US);
Abstract
Pharmaceutical compositions that include an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component are described. The insulin drug is covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1. Methods of treating an insulin deficiency in a subject in need of such treatment using such pharmaceutical compositions are also provided, as are methods of providing such pharmaceutical compositions.