The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2005

Filed:

Jun. 19, 2001
Applicants:

Arvydas Janulaitis, Vilnius, LT;

Komelijus Stankevicius, Vilnius, LT;

Arvydas Lubys, Vilnius, LT;

Algimantas Markauskas, Vilnius, LT;

Inventors:

Arvydas Janulaitis, Vilnius, LT;

Komelijus Stankevicius, Vilnius, LT;

Arvydas Lubys, Vilnius, LT;

Algimantas Markauskas, Vilnius, LT;

Assignee:

Fermentas AB, Vilnius, LT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N009/22 ; C12P019/34 ;
U.S. Cl.
CPC ...
Abstract

A strand-specific polynucleotide nickase comprising an endonuclease which comprises a first subunit and a second subunit and which recognises an asymmetric nucleotide recognition sequence, wherein the first subunit comprises a catalytic domain capable of cleaving one strand of a DNA duplex, and the second subunit is incapable of cleaving the other strand of the DNA duplex.


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