The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Dec. 28, 1999
Applicants:
Jeffrey D. Milbrandt, St. Louis, MO (US);
Robert H. Baloh, St. Louis, MO (US);
Inventors:
Jeffrey D. Milbrandt, St. Louis, MO (US);
Robert H. Baloh, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K039/00 ; A61K039/38 ; A61K038/24 ; C12N005/00 ; A01N037/18 ;
U.S. Cl.
CPC ...
Abstract
Chimeric GDNF family ligands which activate a GFRα/RET are disclosed. Included are chimeras which activate GFRα1/RET but do not activate GFRα2-RET or GFRα3-RET. The chimeras are useful in providing trophic support to a mammalian cell or in producing differentiation of a mammalian cell, or both, particularly when the cell is in a patient suffering from various diseases, in particular Parkinson's Disease.